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교수진

교수정보의 상세 화면-2019
이름 최상돈 학력 박사 전공 생명과학전공(과)
정보	연구실 : 원천관 209 연구실번호 : 2600 이메일 : sangdunchoi@ajou.ac.kr 연구관심분야 : Innate immunity, Toll-like receptor, Systems immunology, Immunomodulator, NF-kB, IkB, ATF3, TRAF6, DNA microarray, Gene expression, RNAi, G protein Ga13, Induced pluripotent stem cells, CRISPR/Cas9 홈페이지1 : http://www.openwetware.org/wiki/Sangdunchoi
학력	졸업연도/학교/학위 1997.12 Texas A&M University 박사 졸업연도/학교/학위 1990.08 연세대학교 석사
경력	2018 – Present Dean of the College of Natural Sciences, Ajou University (자연과학대학 학장) 2018 – Present Director of Basic Science Institute, Ajou University 2012 – 2018 Director of (Priority Research Center) Molecular Science and Technology Research Center, Ajou University (중점연구소 소장) 2011/2/3/7/8 Chair of Department of Biological Science, Ajou University 2006 – Present Professor/Associate Professor, (BK21) Department of Molecular Science and Technology, Ajou University 2000 – 2006 Transcription Analysis Lab Director and Member of Professional Staff, California Institute of Technology, CA, USA 2000 – 2006 Lead Scientist, Alliance for Cellular Signaling (President: Alfred Gilman), USA 1997 – 1999 Postdoctoral Fellow, California Institute of Technology, CA, USA 1993 – 1997 Department of Genetics, Texas A&M University (Ph.D.), College Station, TX, USA 1988 – 1990 Department of Biochemistry, College of Natural Science, Yonsei University (M.S), Seoul, Korea
연구분야	1. Innate Immunity Deciphering Toll-like receptor signaling systems and controlling networks in immune cells; Developing immunomodulators as therapeutic agents 2. Systems Biology Understanding the interactions of functioning components using network perturbations and the measurement of cellular responses 3. Network Analysis Identification of the signal networks using genomics, transcriptomics, proteomics, metabolomics, methylation, RNAi, etc. 4. Stem Cells Induced pluripotent stem cell lines derived from human somatic cells, CRISPR/Cas9
기타	In the Editorial Boards of 1. Scientific Reports 2. PLoS ONE (Academic Editor) 3. Experimental and Molecular Medicine 4. Systems and Synthetic Biology 5. Frontiers in Systems Physiology 6. Genomics & Informatics 7. Journal of Biological Medicine 8. World Journal of Experimental Medicine Editors of the Books 1. Encyclopedia of Signaling Molecules (2nd Edition; 8 Books), 2017 by Springer 2. Encyclopedia of Signaling Molecules (3 Books, 2,150 pages), 2012 by Springer 3. (Editor-in-Chief) Systems Biology Book Series (4 Books), 2011 by Springer 4. Systems Biology for Signaling Networks, 2010 by Springer 5. Introduction to Systems Biology, 2007 by Humana Press Awards 1. Research Award (2018; Ajou University; Cash prize $5,000) 2. Research Award (2017; Ajou University) 3. Research Award (2016; Ajou University; Cash prize $7,500) 4. Cheongsan Award (2015; Korean Society for Biochemistry and Molecular Biology; Plaque & cash prize $5,000) (생화학분자생물학회 청산상) 5. Research Award (2015; Ajou University; Plaque & cash prize) 6. Yulgok Award (2014; Ajou University; Certificate, 6 credits class exemption & cash prize $10,000) (아주대학교 율곡상) 7. Science Foundation Academic Prize (2013; Republic of Korea; Certificate, medal & cash prize $50,000) (대한민국 학술원상) 8. Certificate of Merit (2012; Ajou University; Plaque) 9. Best Paper Award (2007; Korea Genome Organization; Plaque & cash prize) Technology Transfer 1. ㈜젠센 (2018.9; Contract amount $2 millions; Down payment 100,000,000won) 2. ㈜젠센 (2018.7; Contract amount $2 millions; Down payment 20,000,000won) 3. J2H Biotech (2018.12; Contract amount $0.5 million)
논문 및 연구활동	연구활동(주요논문) [논문] ACHEK ASMA, GUI XIANGAI, SHAH MASAUD, 권혁권, 김문석, 서지영, 신현준, 유태현, 이병성, 조은영, 김동진, 이상호, 최상돈, Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model , JOURNAL OF MEDICINAL CHEMISTRY , Vol.62 , No.14 , pp.6495 -6511 (Jul, 2019) [논문] 권혁권, ACHEK ASMA, GUI XIANGAI, PANNERSELVAM SURESH, PATRA MAHESH CHANDRA, 신현준, Dae-Hyun Hahm, Dong-Jin Kim, Francis Y. Lee, Kyoung Soo Kim, Riwon Hong, Sang Ho Lee, Suk-Jong Song, Yang Gyun Kim, 최상돈, A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice , EXPERIMENTAL AND MOLECULAR MEDICINE , Vol.51 , No.50 , pp.1 -19 (Apr, 2019) [논문] ANWAR MUHAMMAD AYAZ, SHAH MASAUD, Jason Kim, 최상돈, Recent clinical trends in Toll?like receptor targeting therapeutics , MEDICINAL RESEARCH REVIEWS , pp.1 -38 (Nov, 2018) [논문] 이재혁, 권혁권, 김재호, 남광현, 신현준, 최상돈, Quasi-Stem Cells Derived from Human Somatic Cells by Chemically Modified Carbon Nanotubes , ACS APPLIED MATERIALS & INTERFACES , Vol.2018 , No.10 , pp.8417 -8425 (Mar, 2018) [논문] SHAH MASAUD, 박설희, 신현준, ACHEK ASMA, ANWAR MUHAMMAD AYAZ, 권혁권, 유태현, 이병성, 조혜영, 최상돈, TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation , BIOMATERIALS , Vol.126 , pp.49 -60 (May, 2017) 국제학술논문지 [논문] 이소연, 김신아, 김영훈, 서지영, 주현진, 지윤배, 김한수, 이해방, 김문석, 최상돈, Enhanced intra-articular therapy for rheumatoid arthritis using click-crosslinked hyaluronic acid hydrogels loaded with toll-like receptor antagonizing peptides , Acta Biomaterialia , pp.188 -205 (Nov, 2023) [논문] 김영훈, 김신아, 김은하, 주현진, 최상돈, 한민지, 박용두, 최학수, 김문석, In-situ wound healing by SDF-1-mimic peptide-loaded click crosslinked hyaluronic acid scaffold , JOURNAL OF CONTROLLED RELEASE , pp.420 -434 (Nov, 2023) [논문] RATHER BILAL AHMAD, Achek Asma, FAROOQ MARIYA, 최상돈, Accelerated NLRP3 inflammasome-inhibitory peptide design using a recurrent neural network model and molecular dynamics simulations , Computational and Structural Biotechnology Journal , Vol.21 , No.2023 , pp.4825 -4835 (Sep, 2023) [논문] RATHER BILAL AHMAD, 최상돈, Alice Burleigh, Andrey Gagunashvili, Atul Kumar, Austen J. J. Worth, Barbara Jensen, Despina Eleftheriou, Ebun Omoyinmi, Elizabeth Whittaker, Evangelos Bellos, Fiona Price-Kuehne, Jethro A. Herberg, Kimberly C. Gilmour, Kshitij Mankad, Marios Kaliakatsos, Mohammad W. Bahar, Paul A. Brogan, Paul Torpiano, Vanessa Sancho-Shimizu, Ying Hong, Samantha Cooray, Neuroinflammation, autoinflammation, splenomegaly and anemia caused by bi-allelic mutations in IRAK4 , Frontiers in Immunology , Vol.14 , pp.1 -16 (Sep, 2023) [논문] Muhammad Ayaz Anwar, HASEEB MUHAMMAD, 최상돈, Kwang Pyo Kim, P176S Mutation Rewires Electrostatic Interactions That Alter Maspin Functionality , ACS Omega , Vol.8 , No.31 , pp.28258 -28267 (Aug, 2023) [논문] KHAN ABDUL WAHEED, FAROOQ MARIYA, 황문정, Muhammad Haseeb, 최상돈, Autoimmune Neuroinflammatory Diseases: Role of Interleukins , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.9 , No.7960 , pp.1 -19 (Apr, 2023) [논문] PIRZADA RAMEEZ HASSAN, QAYYUM NAILA, RATHER BILAL AHMAD, 최상돈, Modeling structure–activity relationships with machine learning to identify GSK3-targeted small molecules as potential COVID-19 therapeutics , Frontiers in Endocrinology , Vol.14 , No.1084327 , pp.1 -14 (Mar, 2023) [논문] 지윤배, 김희은, 노정현, 이소연, 주현진, 최상돈, Park Kinam, 이해방, 김문석, Preparation and evaluation of injectable microsphere formulation for longer sustained release of donepezil , JOURNAL OF CONTROLLED RELEASE , pp.43 -58 (Mar, 2023) [논문] 노준기, 양예영, 이왕희, 권소희, 김수하, 김형모, 박영환, 송유진, 유소희, 윤주환, 이슬비, 이은영, 최상돈, 최양선, 최홍서, 한지혜, 김정웅, 김환, 박재형, 송우근, 오영수, 이은경, 이준호, 정명우, 한숙영, 한화승, 김욱, 김은하, Hyaluronic Acid Nanoparticles as a TopicalAgent for Treating Psoriasis , ACS Nano , Vol.16 , No.12 , pp.20057 -20074 (Nov, 2022) [논문] JAVAID NASIR, PATRA MAHESH CHANDRA, 조다은, BATOOL MARIA, 김문석, Gwang Muk Choi, Yoongeun Kim, 최상돈, 함대현, An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice , SCIENCE SIGNALING , pp.1 -16 (Nov, 2022) [논문] 이강곤, PIRZADA RAMEEZ HASSAN, SHAH MASAUD, Ana Rita M. P. Santos, Jongseong Kim, Myeongjin Song, Yong Guk Kang, Yun Jin Chae, 최상돈, Yongdoo Park, Efficacy Evaluation of SDF-1α-Based Polypeptides in an Acute Myocardial Infarction Model Using Structure-Based Drug Design , ACS Biomaterials Science & Engineering , pp.4486 -4496 (Sep, 2022) [논문] JAVAID NASIR, 최상돈, An Alternate Approach to Generate Induced Pluripotent Stem Cells with Precise CRISPR/Cas9 Tool , Stem Cells International , pp.1 -17 (Sep, 2022) [논문] MUGHAL ABDUL MANAN, PIRZADA RAMEEZ HASSAN, Haseeb Muhammad, 최상돈, Toll-like Receptor Mediation in SARS-CoV-2: Therapeutic Approach , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -25 (Sep, 2022) [논문] 김희은, 신기루, 김재호, 주현진, 최상돈, Hak Soo Choi, 김문석, Injectable click-crosslinked hydrogel containing resveratrol to improve the therapeutic effect in triple negative breast cancer , MATERIALS TODAY BIO , pp.100386 -100386 (Aug, 2022) [논문] RATHER BILAL AHMAD, 최상돈, Unraveling the Tomaralimab Epitope on the Toll-like Receptor 2 via Molecular Dynamics and Deep Learning , ACS OMEGA , Vol.7 , pp.28226 -28237 (Aug, 2022) [논문] 이혜연, 지윤배, 김영훈, 김재호, 이소연, 최상돈, 나건, 김문석, Electrostatically optimized adapalene-loaded emulsion for the treatment of acne vulgaris , MATERIALS TODAY BIO , pp.100339 -100339 (Jul, 2022) [논문] FAROOQ MARIYA, KHAN ABDUL WAHEED, RATHER BILAL AHMAD, 김문석, 최상돈, Therapeutic Targeting of Innate Immune Receptors Against SARS-CoV-2 Infection , FRONTIERS IN PHARMACOLOGY , pp.1 -22 (Jun, 2022) [논문] KHAN ABDUL WAHEED, FAROOQ MARIYA, HASEEB MUHAMMAD, 최상돈, Role of Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action , CELLS , pp.1 -48 (Apr, 2022) [논문] HASEEB MUHAMMAD, JAVAID NASIR, YASMEEN FARZANA, 김문석, 윤주환, 정의석, 한지혜, 서지연, 신호철, 허재경, 김욱, 최상돈, Novel Small-Molecule Inhibitor of NLRP3 Inflammasome Reverses Cognitive Impairment in an Alzheimer’s Disease Model , ACS CHEMICAL NEUROSCIENCE , pp.818 -833 (Feb, 2022) [논문] BATOOL MARIA, 김문석, 최상돈, Structural insights into the distinctive RNA recognition and therapeutic potentials of RIG‐I‐like receptors , MEDICINAL RESEARCH REVIEWS , pp.1 -27 (Jan, 2022) [논문] 백욱영, 손인옥, 이상원, 전기웅, 최상돈, 최양선, 서창희, Toll-Like Receptor Signaling Inhibitory Peptide Improves Inflammation in Animal Model and Human Systemic Lupus Erythematosus , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -13 (Nov, 2021) [논문] JAVAID NASIR, 최상돈, CRISPR/Cas System and Factors Affecting Its Precision and Efficiency , FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY , pp.1 -25 (Nov, 2021) [논문] FAROOQ MARIYA, KHAN ABDUL WAHEED, 김문석, 최상돈, The Role of Fibroblast Growth Factor (FGF) Signaling in Tissue Repair and Regeneration , CELLS , pp.1 -21 (Nov, 2021) [논문] 신기루, 김재호, 김희은, 최상돈, 김문석, Advances in Injectable In Situ-Forming Hydrogels for Intratumoral Treatment , PHARMACEUTICS , pp.1953 -1953 (Nov, 2021) [논문] 박승훈, Shah Masaud, 민병현, 주현진, 지윤배, Hak Soo Choi, 김문석, 최상돈, Endogenous Stem Cell-Based In Situ Tissue Regeneration Using Electrostatically Interactive Hydrogel with a Newly Discovered Substance P Analog and VEGF-Mimicking Peptide , SMALL , pp.2103244 -2103244 (Oct, 2021) [논문] FAROOQ MARIYA, BATOOL MARIA, 김문석, 최상돈, Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies , FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY , pp.1 -15 (Oct, 2021) [논문] 지윤배, 강영지, 박준영, 이설하, 주현진, 최상돈, 김문석, 이분열, Scaffold printing using biodegradable poly(1,4-butylene carbonate) ink: printability, in vivo physicochemical properties, and biocompatibility , MATERIALS TODAY BIO , pp.100129 -100129 (Sep, 2021) [논문] RATHER BILAL AHMAD, AIN QURAT UL, BATOOL MARIA, 김문석, 최상돈, Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -13 (Aug, 2021) [논문] JAVAID NASIR, Fang-Sik Che, Hiroyuki Hirai, 최상돈, Molecular Basis for the Activation of Human Innate Immune Response by the Flagellin Derived from Plant-Pathogenic Bacterium, Acidovorax avenae , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -13 (Jun, 2021) [논문] 김다연, 김재호, 주현진, 최상돈, 김문석, Injectable in situ forming hydrogel gene depot to improve the therapeutic effect of STAT3 shRNA , BIOMATERIALS SCIENCE , pp.4459 -4472 (Jun, 2021) [논문] RATHER BILAL AHMAD, BATOOL MARIA, 김문석, 최상돈, Computational-Driven Epitope Verification and Affinity Maturation of TLR4-Targeting Antibodies , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -17 (Jun, 2021) [논문] PIRZADA RAMEEZ HASSAN, BATOOL MARIA, HASEEB MUHAMMAD, 김문석, 최상돈, Remdesivir and Ledipasvir among the FDA-Approved Antiviral Drugs Have Potential to Inhibit SARS-CoV-2 Replication , CELLS , pp.1 -16 (Apr, 2021) [논문] HASEEB MUHAMMAD, QAYYUM NAILA, 김문석, 최상돈, Role of Thioredoxin-Interacting Protein in Diseases and Its Therapeutic Outlook , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -21 (Mar, 2021) [논문] NGUYEN THI THU THAO, 강영지, 신기루, 이설하, 최상돈, 김문석, Preparation of Electrospun Small Intestinal Submucosa/Poly(caprolactone- co-Lactide- co-glycolide) Nanofiber Sheet as a Potential Drug Carrier , PHARMACEUTICS , pp.253 -253 (Feb, 2021) [논문] Su Woong Jung, 최상돈, Ju-Young Moon, Jung-Woo Seo, Seon Hwa Park, Yang Gyun Kim, Sang-Ho Lee, A Cell-Penetrating Peptide That Blocks Toll-Like Receptor Signaling Protects Kidneys against Ischemia-Reperfusion Injury , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -12 (Feb, 2021) [논문] JAVAID NASIR, PHAM LE HOAI THUONG, 최상돈, Functional Comparison between VP64-dCas9-VP64 and dCas9-VP192 CRISPR Activators in Human Embryonic Kidney Cells , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.22 , No.397 , pp.1 -16 (Jan, 2021) [논문] JAVAID NASIR, PATRA MAHESH CHANDRA, YASMEEN FARZANA, 서하나, 최상돈, A Rational Insight into the Eect of Dimethyl Sulfoxide on TNF-a Activity , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.21 , No.24 , pp.1 -14 (Dec, 2020) [논문] SHAH MASAUD, RATHER BILAL AHMAD, 최상돈, 우현구, Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization , COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL , Vol.18 , pp.3402 -3414 (Nov, 2020) [논문] YASMEEN FARZANA, JAVAID NASIR, 김문석, 서하나, 최상돈, Therapeutic Interventions into Innate Immune Diseases by Means of Aptamers , PHARMACEUTICS , Vol.12 , No.955 , pp.1 -30 (Oct, 2020) [논문] RATHER BILAL AHMAD, 최상돈, Asha Bhagat, Gifty Sawhney, Parveen Kumar, Reyaz Hassan Mir, Rohini Verma, Sanjay M Jachak, Soni Ranjana, Sreedhar Madishetti, Zabeer Ahmed, Mubashir Hussain Masoodi, Origanum vulgare L.: In-vitro Assessment of Cytotoxicity, Molecular Docking Studies, Antioxidant and Anti-inflammatory Activity in LPS Stimulated RAW 264.7 Cells , MEDICINAL CHEMISTRY , Vol.16 , pp.1 -11 (Sep, 2020) [논문] 김효섭, 이빛나, 최상돈, 김문석, 김재호, Behavior of Muscle-Derived Stem Cells on Silica Nanostructured Substrates , NANOMATERIALS , pp.1651 -1651 (Aug, 2020) [논문] ACHEK ASMA, PATRA MAHESH CHANDRA, 김기영, PANNERSELVAM SURESH, 김욱, 김은하, 백욱영, 서창희, 성준, 신현준, 이왕희, 정의석, 조은영, 최상돈, A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inﬂammation and Alleviates Autoimmune Disease Symptoms in Murine Models , CELLS , Vol.9 , No.1648 , pp.1 -21 (Jul, 2020) [논문] ACHEK ASMA, SHAH MASAUD, 김기영, 김순선, 김욱, 백욱영, 서창희, 이왕희, 정재연, 조은영, 최양선, 김동진, 이상호, 최상돈, The αC helix of TIRAP holds therapeutic potential in TLR-mediated autoimmune diseases , BIOMATERIALS , Vol.245 , No.119974 , pp.1 -17 (Jul, 2020) [논문] PATRA MAHESH CHANDRA, BATOOL MARIA, HASEEB MUHAMMAD, 최상돈, A Computational Probe into the Structure and Dynamics of the Full-Length Toll-Like Receptor 3 in a Phospholipid Bilayer , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.21 , No.2857 , pp.1 -25 (Apr, 2020) [논문] ACHEK ASMA, PATRA MAHESH CHANDRA, PHAM LE HOAI THUONG, SHAH MASAUD, 권혁권, 김기영, 김욱, 백욱영, 서창희, 이왕희, 최양선, 함대현, 홍리원, 최상돈, A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models , EBIOMEDICINE , Vol.52 , No.102645 , pp.1 -15 (Feb, 2020) [논문] AIN QURAT UL, BATOOL MARIA, 최상돈, TLR4-targeting Therapeutics: Structural Basis and Computer-aided Drug Discovery Approaches , MOLECULES , Vol.25 , No.627 , pp.1 -17 (Jan, 2020) [논문] JAVAID NASIR, 최상돈, Toll-like Receptors from the Perspective of Cancer Treatment , CANCERS , Vol.12 , No.297 , pp.1 -32 (Jan, 2020) [논문] PIRZADA RAMEEZ HASSAN, JAVAID NASIR, 최상돈, The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions , GENES , Vol.11 , No.131 , pp.1 -21 (Jan, 2020) [논문] SHAH MASAUD, Muhammad Junaid, 최상돈, Aamir Mehmood, Abbas Khan, Aman Chandra Kaushik, Arif Ali, Asma Sindhoo Nangraj, Cheng-Dong Li, Muhammad Tahir Khan, Dong-Qing Wei, Structural-dynamic insights into the H. pylori cytotoxin-associated gene A (CagA) and its abrogation to interact with the tumor suppressor protein ASPP2 using decoy peptides , JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , Vol.37 , No.15 , pp.4035 -4050 (Dec, 2019) [논문] HASEEB MUHAMMAD, AIN QURAT UL, PIRZADA RAMEEZ HASSAN, 최상돈, Wnt Signaling in the Regulation of Immune Cell and Cancer Therapeutics , CELLS , Vol.8 , No.1380 , pp.1 -35 (Nov, 2019) [논문] Prachetash Ghosh, Shah Masaud, 최상돈, Hamid Iqbal, Kyeong Kyu Kim, Sang-Sang Park, Subramaniyam Ravichandran, Dong Kwon Rhee, Pneumococcal VncR Strain-Specifically Regulates Capsule Polysaccharide Synthesis , FRONTIERS IN MICROBIOLOGY , Vol.10 , No.2279 , pp.1 -13 (Oct, 2019) [논문] JAVAID NASIR, YASMEEN FARZANA, 최상돈, Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods , PHARMACEUTICS , Vol.11 , No.441 , pp.1 -30 (Sep, 2019) [논문] ACHEK ASMA, GUI XIANGAI, SHAH MASAUD, 권혁권, 김문석, 서지영, 신현준, 유태현, 이병성, 조은영, 김동진, 이상호, 최상돈, Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model , JOURNAL OF MEDICINAL CHEMISTRY , Vol.62 , No.14 , pp.6495 -6511 (Jul, 2019) [논문] 서지영, 김경숙 , 김재호, 민병현, 박승훈, 박준영, 지윤배, 최상돈, 최학수, 김문석, An injectable, click-crosslinked,cytomodulin-modified hyaluronic acid hydrogel for cartilage tissue engineering , NPG ASIA MATERIALS , pp.30 -30 (Jun, 2019) [논문] BATOOL MARIA, RATHER BILAL AHMAD, 최상돈, A Structure-Based Drug Discovery Paradigm , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.20 , No.2783 , pp.1 -18 (Jun, 2019) [논문] 김한결, ANWAR MUHAMMAD AYAZ, 최상돈, Association of BUD13-ZNF259-APOA5-APOA1-SIK3 cluster polymorphism in 11q23.3 and structure of APOA5 with increased plasma triglyceride levels in a Korean population , SCIENTIFIC REPORTS , Vol.9 , pp.1 -12 (Jun, 2019) [논문] 윤사라, SHAH MASAUD, 김성주, 이은주, 최상돈, 최지혜, 우현구, EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression. , EXPERIMENTAL AND MOLECULAR MEDICINE (Jun, 2019) [논문] RATHER BILAL AHMAD, Shah Masaud, 최상돈, Oceans as a Source of Immunotherapy , MARINE DRUGS , Vol.17 , No.5 , pp.1 -46 (May, 2019) [논문] PATRA MAHESH CHANDRA, SHAH MASAUD, 최상돈, Toll-like receptor-induced cytokines as immunotherapeutic targets in cancers and autoimmune diseases , SEMINARS IN CANCER BIOLOGY , pp.1 -22 (May, 2019) [논문] 권혁권, ACHEK ASMA, GUI XIANGAI, PANNERSELVAM SURESH, PATRA MAHESH CHANDRA, 신현준, Dae-Hyun Hahm, Dong-Jin Kim, Francis Y. Lee, Kyoung Soo Kim, Riwon Hong, Sang Ho Lee, Suk-Jong Song, Yang Gyun Kim, 최상돈, A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice , EXPERIMENTAL AND MOLECULAR MEDICINE , Vol.51 , No.50 , pp.1 -19 (Apr, 2019) [논문] YESUDHAS DHANUSHA, Muhammad Ayaz Anwar, 최상돈, Structural mechanism of DNA-mediated Nanog–Sox2 cooperative interaction , RSC ADVANCES , Vol.2019 , No.9 , pp.8121 -8130 (Mar, 2019) [논문] Soo Min Han, 최상돈, Hunjoo Ha, Hye-Myung Ryu, Jinjoo Suh, Kong-Joo Lee, Soon-Youn Choi, Yong-Lim Kim, Joo Young Huh, Network-based integrated analysis of omics data reveal novel players of TGF-β1-induced EMT in human peritoneal mesothelial cells , SCIENTIFIC REPORTS , Vol.9 , No.1497 , pp.1 -12 (Feb, 2019) [논문] HASEEB MUHAMMAD, ANWAR MUHAMMAD AYAZ, 최상돈, Molecular Interactions Between Innate and Adaptive Immune Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications , FRONTIERS IN IMMUNOLOGY , Vol.9 , pp.1 -16 (Nov, 2018) [논문] ANWAR MUHAMMAD AYAZ, SHAH MASAUD, Jason Kim, 최상돈, Recent clinical trends in Toll?like receptor targeting therapeutics , MEDICINAL RESEARCH REVIEWS , pp.1 -38 (Nov, 2018) [논문] Prachetash Ghosh, SHAH MASAUD, 최상돈, Sangho Lee, Truc Thanh Luong, Trung Thanh Thach, Dong-Kwon Rhee, Adenylate kinase potentiates the capsular polysaccharide by modulating Cps2D in Streptococcus pneumoniae D39. , EXPERIMENTAL AND MOLECULAR MEDICINE , Vol.50 , No.116 , pp.1 -14 (Sep, 2018) [논문] Mojtaba Khajeh Alizadeh Attar, Muhammad Ayaz Anwar, 최상돈, Mahsa Eskian, Mahsa Keshavarz?Fathi, Nima Rezaei, Basic understanding and therapeutic approaches to target toll?like receptors in cancerous microenvironment and metastasis , MEDICINAL RESEARCH REVIEWS , Vol.38 , No.5 , pp.1469 -1484 (Sep, 2018) [논문] 이재혁, 권혁권, 김재호, 남광현, 신현준, 최상돈, Quasi-Stem Cells Derived from Human Somatic Cells by Chemically Modified Carbon Nanotubes , ACS APPLIED MATERIALS & INTERFACES , Vol.2018 , No.10 , pp.8417 -8425 (Mar, 2018) [논문] PATRA MAHESH CHANDRA, BATOOL MARIA, 권혁권, 최상돈, Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer , FRONTIERS IN IMMUNOLOGY , Vol.9 , No.489 , pp.1 -15 (Mar, 2018) [논문] PATRA MAHESH CHANDRA, 최상돈, Insight into Phosphatidylinositol-Dependent Membrane Localization of the Innate Immune Adaptor Protein Toll/Interleukin 1 Receptor Domain-Containing Adaptor Protein , FRONTIERS IN IMMUNOLOGY , Vol.9 , No.75 , pp.1 -16 (Jan, 2018) [논문] 박예섭, 최운종, NASIR ABDUL, 최상돈, 최상진, Nguyen Hoai Nam, 김경진, 심증엽, 이선구, 정규열, 유태현, 박성훈, Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD+, for enhancing the production of 3-hydroxypropionic acid , SCIENTIFIC REPORTS , Vol.7 , No.1 , pp.17155(1) -17155(12) (Dec, 2017) [논문] YESUDHAS DHANUSHA, Muhammad Ayaz Anwar, PANNERSELVAM SURESH, 김한결, 최상돈, Evaluation of Sox2 binding affinities for distinct DNA patterns using steered molecular dynamics simulation , FEBS OPEN BIO , pp.1 -18 (Oct, 2017) [논문] BATOOL MARIA, PATRA MAHESH CHANDRA, SHAH MASAUD, YESUDHAS DHANUSHA, 최상돈, Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism , SCIENTIFIC REPORTS , Vol.7 , pp.1 -14 (Sep, 2017) [논문] JAVAID NASIR, 최상돈, Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets , GENES , Vol.8 , No.196 , pp.1 -37 (Aug, 2017) [논문] YESUDHAS DHANUSHA, BATOOL MARIA, Muhammad Ayaz Anwar, PANNERSELVAM SURESH, 최상돈, Proteins Recognizing DNA: Structural Uniqueness and Versatility of DNA-Binding Domains in Stem Cell Transcription Factors , GENES , Vol.8 , No.192 , pp.1 -22 (Aug, 2017) [논문] Durai Prasannavenkatesh, ACHEK ASMA, PANNERSELVAM SURESH, Rajiv Gandhi, YESUDHAS DHANUSHA, 권혁권, 신현준, 노경태, 최지원, 최상돈, Toll-like receptor 2 antagonists identified through virtual screening and experimental validation , FEBS JOURNAL , Vol.284 , pp.2264 -2283 (Jul, 2017) [논문] SHAH MASAUD, 최상돈, Toll-like Receptor-Dependent Negative effects of Opioids: A Battle between Analgesia and Hyperalgesia , FRONTIERS IN IMMUNOLOGY , Vol.8 , No.642 , pp.1 -7 (May, 2017) [논문] SHAH MASAUD, 박설희, 신현준, ACHEK ASMA, ANWAR MUHAMMAD AYAZ, 권혁권, 유태현, 이병성, 조혜영, 최상돈, TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation , BIOMATERIALS , Vol.126 , pp.49 -60 (May, 2017) [논문] ANWAR MUHAMMAD AYAZ, 최상돈, Structure-Activity Relationship in TLR4 Mutations: Atomistic Molecular Dynamics Simulations and Residue Interaction Network Analysis , SCIENTIFIC REPORTS , No.7 , pp.43807(1) -43807(14) (Mar, 2017) [논문] Arunkumar Rengaraj, YESUDHAS DHANUSHA, 최상돈, Balaji Subbiah, Eung-Soo Kim, Hema Shenpagam N., Hyung Joong Yun, Soonjo Kwon, Young-Kyu Han, Yuvaraj Haldorai, Yun Suk Huh, PAMAM/5-fluorouracil drug conjugate for targeting E6 and E7 oncoproteins in cervical cancer: a combined experimental/in silico approach , RSC ADVANCES , Vol.2017 , No.7 , pp.5046 -5054 (Jan, 2017) [논문] Smilin Bell Aseervatham G, 최상돈, Jayalakshmi Krishnan, Ruckmani K, Cigarette smoke and related risk factors in neurological disorders: An update , BIOMEDICINE & PHARMACOTHERAPY , Vol.85 , pp.79 -86 (Jan, 2017) [논문] SHAH MASAUD, ANWAR MUHAMMAD AYAZ, YESUDHAS DHANUSHA, Jayalakshmi Krishnan, 최상돈, A structural insight into the negative effects of opioids in analgesia by modulating the TLR4 signaling: An in silico approach , SCIENTIFIC REPORTS , Vol.6 , No.39271 , pp.1 -15 (Dec, 2016) [논문] PANNERSELVAM SURESH, ACHEK ASMA, Durai Prasannavenkatesh, YESUDHAS DHANUSHA, 권혁권, 최상돈, Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study , RSC ADVANCES , Vol.6 , pp.100804 -100819 (Nov, 2016) [논문] PATRA MAHESH CHANDRA, 최상돈, Recent Progress in the Molecular Recognition and Therapeutic Importance of Interleukin-1 Receptor-Associated Kinase 4 , MOLECULES , Vol.21 , No.11 , pp.1529 -1529 (Nov, 2016) [논문] BATOOL MARIA, ANWAR MUHAMMAD AYAZ, 최상돈, Toll-like receptors targeting technology for the treatment of lymphoma , EXPERT OPINION ON DRUG DISCOVERY , Vol.11 , No.11 , pp.1047 -1059 (Nov, 2016) [논문] 신현준, ANWAR MUHAMMAD AYAZ, 권혁권, 이재혁, 최상돈, Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells , SCIENTIFIC REPORTS , No.6 , pp.34064 -34064 (Sep, 2016) [논문] ANWAR MUHAMMAD AYAZ, SHAH MASAUD, YESUDHAS DHANUSHA, 최상돈, Structural and conformational insights into SOX2/OCT4-bound enhancer DNA: a computational perspective , RSC ADVANCES , Vol.2016 , No.6 -90153 (Sep, 2016) [논문] Otto Morris, Shaherin Basith, 최상돈, Andrea Chai, Celia Domingues, Christopher Runchel, Giuseppa Pennetta, Haiyang Chen, Nicolas Buchon, Tencho Tenev, Xi Liu, Pascal Meier, Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense , CELL HOST & MICROBE , Vol.20 , No.3 , pp.283 -295 (Sep, 2016) [논문] ACHEK ASMA, YESUDHAS DHANUSHA, 최상돈, Toll-like receptors: promising therapeutic targets for inflammatory diseases , ARCHIVES OF PHARMACAL RESEARCH , Vol.39 , No.8 , pp.1032 -1049 (Sep, 2016) [논문] PHUKAN GEETIKA, 강엽, 신태환, 심점순, 이수환, 최상돈, M. Maral Mouradian, 강성호, 김영만, 김형식, 백만정, 이진규, 이광, Silica-coated magnetic nanoparticles impair proteasome activity and increase the formation of cytoplasmic inclusion bodies in vitro , SCIENTIFIC REPORTS , Vol.6 , No.29095 , pp.28829 -28829 (Jul, 2016) [논문] PATRA MAHESH CHANDRA, 최상돈, Recent progress in the development of Toll-like receptor (TLR) antagonists , EXPERT OPINION ON THERAPEUTIC PATENTS , Vol.26 , No.6 , pp.719 -730 (May, 2016) [논문] ANWAR MUHAMMAD AYAZ, SHAH MASAUD, 김재호, 최상돈, Advances in Antiviral Therapies Targeting Toll-like Receptors , EXPERT OPINION ON INVESTIGATIONAL DRUGS , Vol.25 , No.4 , pp.437 -453 (Apr, 2016) [논문] ANWAR MUHAMMAD AYAZ, 김송미, 최상돈, The triumph of chemically enhanced cellular reprogramming: a patent review , EXPERT OPINION ON THERAPEUTIC PATENTS , Vol.26 , No.2 , pp.265 -280 (Feb, 2016) [논문] YESUDHAS DHANUSHA, ANWAR MUHAMMAD AYAZ, Durai Prasannavenkatesh, PANNERSELVAM SURESH, SHAH MASAUD, 최상돈, Structural Mechanism behind Distinct Efficiency of Oct4/Sox2 Proteins in Differentially Spaced DNA Complexes , PLoS ONE , Vol.11 , No.1 , pp.1 -21 (Jan, 2016) [논문] 신현준, ACHEK ASMA, GUI XIANGAI, 권혁권, 김재호, 이재혁, 최상돈, Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53 , SCIENTIFIC REPORTS , Vol.5 , No.15798 , pp.1 -17 (Nov, 2015) [논문] 권혁권, PANNERSELVAM SURESH, 권민철, 김재호, 박설희, 신현준, 이재혁, 김상건, 이찬규, 최상돈, Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells , TOXICOLOGICAL SCIENCES , Vol.148 , No.1 , pp.204 -219 (Nov, 2015) [논문] 권혁권, 김재호, 신현준, 이재혁, 최상돈, Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death , SCIENTIFIC REPORTS , Vol.5 , No.15623 , pp.1 -15 (Oct, 2015) [논문] 권지웅, 권혁권, ANWAR MUHAMMAD AYAZ, 신현준, 최용민, 최상돈, Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB , SCIENTIFIC REPORTS , Vol.5 , No.14470 , pp.1 -9 (Sep, 2015) [논문] Durai Prasannavenkatesh, BATOOL MARIA, SHAH MASAUD, 최상돈, Middle East respiratory syndrome coronavirus: transmission, virology, and therapeutic targeting to aid in outbreak control , EXPERIMENTAL AND MOLECULAR MEDICINE , Vol.47 , pp.1 -10 (Aug, 2015) [논문] SHAH MASAUD, ANWAR MUHAMMAD AYAZ, 박설희, Syyada Samra Jafri, 최상돈, In silico mechanistic analysis of IRF3 inactivation and high-risk HPV E6 species-dependent drug response , SCIENTIFIC REPORTS , Vol.5 , No.13446 , pp.1 -14 (Aug, 2015) [논문] Durai Prasannavenkatesh, PANNERSELVAM SURESH, YESUDHAS DHANUSHA, ANWAR MUHAMMAD AYAZ, GOSU Vijayakumar, 최상돈, A Combined Molecular Docking/Dynamics Approach to Probe the Binding Mode of Cancer Drugs with Cytochrome P450 3A4 , MOLECULES , Vol.20 , No.8 , pp.14915 -14935 (Aug, 2015) [논문] 김한결, 최용민, ANWAR MUHAMMAD AYAZ, 권지웅, 권혁권, 김형중, 김환명, 심우영, 김형식, 정효빈, 황대희, 최상돈, Mechanism of Cisplatin-induced Cytotoxicity is Correlated to Impaired Metabolism due to Mitochondrial ROS Generation , PLoS ONE , Vol.10 , No.8 , pp.1 -21 (Aug, 2015) [논문] 이병성, 신승건, 이분열, 전종엽, 최상돈, 장경순, 유태현, Incorporation of Unnatural Amino Acids in Response to the AGG Codon , ACS CHEMICAL BIOLOGY , Vol.10 , No.7 , pp.1648 -1653 (Jul, 2015) [논문] Durai Prasannavenkatesh, BATOOL MARIA, 최상돈, Structure and Effects of Cyanobacterial Lipopolysaccharides , MARINE DRUGS , Vol.13 , No.7 , pp.4217 -4230 (Jul, 2015) [논문] ANWAR MUHAMMAD AYAZ, PANNERSELVAM SURESH, SHAH MASAUD, 최상돈, Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection , SCIENTIFIC REPORTS , Vol.5 , No.7657 , pp.1 -11 (Jan, 2015) [논문] Truc Thanh Luong, 최상돈, Cuong Thach Nguyen, David E. Briles, Eun-Hye Kim, Jong Phil Bak, Suhkneung Pyo, Dong-Kwon Rhee, Ethanol-Induced Alcohol Dehydrogenase E (AdhE) Potentiates Pneumolysin in Streptococcus pneumoniae , INFECTION AND IMMUNITY , Vol.83 , No.1 , pp.108 -119 (Jan, 2015) [논문] Chan Gyu Lee, 권혁권, 최상돈, Dal Woong Choi, Hyun Joo Kim, Il Je Cho, Jin Geol Kim, Se Jin Hwang, Won Dong Kim, Woo Hyung Lee, Sang Geon Kim, Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury , KIDNEY INTERNATIONAL , Vol.86 , No.5 , pp.943 -953 (Nov, 2014) [논문] GOSU Vijayakumar, 최상돈, Structural dynamic analysis of apo and ATP-bound IRAK4 kinase , SCIENTIFIC REPORTS , Vol.4 , No.5748 , pp.5748-1 -5748-13 (Jul, 2014) [논문] YESUDHAS DHANUSHA, ANWAR MUHAMMAD AYAZ, GOSU Vijayakumar, 최상돈, Multiple roles of toll-like receptor 4 in colorectal cancer , FRONTIERS IN IMMUNOLOGY , Vol.5 , No.334 , pp.1 -10 (Jul, 2014) [논문] 최용민, ANWAR MUHAMMAD AYAZ, 권지웅, 김한결, 조혜영, 최상돈, ATF3 attenuates cyclosporin A-induced nephrotoxicity by downregulating CHOP in HK-2 cells , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.448 , No.2 , pp.182 -188 (May, 2014) [논문] ANWAR MUHAMMAD AYAZ, 최상돈, Gram-Negative Marine Bacteria: Structural Features of Lipopolysaccharides and Their Relevance for Economically Important Diseases , MARINE DRUGS , Vol.12 , No.5 , pp.2485 -2514 (Apr, 2014) [논문] PANNERSELVAM SURESH, 최상돈, Nanoinformatics: Emerging Databases and Available Tools , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Vol.15 , No.5 , pp.7158 -7182 (Apr, 2014) [논문] Durai Prasannavenkatesh, Rajiv Gandhi, 최상돈, Structure and dynamic behavior of Toll-like receptor 2 subfamily triggered by malarial glycosylphosphatidylinositols of Plasmodium falciparum , FEBS JOURNAL , Vol.280 , No.23 , pp.6196 -6212 (Dec, 2013) [논문] Eun-Hye Kim, 이수철, 최상돈, Cuong Thach Nguyen, In-Hye Kim, Jung-Ah Ha, Kwang-Tae Choi, Mi-Jeong Lee, Suhkneung Pyo, Dong-Kwon Rhee, Anti-oxidative stress effect of red ginseng in the brain is mediated by peptidyl arginine deiminase type IV (PADI4) repression via estrogen receptor (ER) β up-regulation , JOURNAL OF ETHNOPHARMACOLOGY , Vol.148 , No.2 , pp.474 -485 (Jul, 2013) [논문] ANWAR MUHAMMAD AYAZ, Basith Shaherin, 최상돈, Negative regulatory approaches to the attenuation of Toll-like receptor signaling , EXPERIMENTAL AND MOLECULAR MEDICINE , Vol.45 (Feb, 2013) [논문] Basith Shaherin, Balachandran Manavalan, GOSU Vijayakumar, 최상돈, Evolutionary, Structural and Functional Interplay of the IκB Family Members , PLoS ONE , Vol.8 , No.1 (Jan, 2013) [논문] Jayalakshmi Krishnan, Basith Shaherin, 최상돈, Advances in Toll-like Receptor Signaling , Advances in Systems Biology , Vol.1 , No.1 , pp.5 -15 (Dec, 2012) [논문] GOSU Vijayakumar, Basith Shaherin, Durai Prasannavenkatesh, 최상돈, Molecular Evolution and Structural Features of IRAK Family Members , PLoS ONE , Vol.7 , No.11 (Nov, 2012) [논문] GOSU Vijayakumar, Basith Shaherin, 권오필, 최상돈, Therapeutic Applications of Nucleic Acids and Their Analogues in Toll-like Receptor Signaling , MOLECULES , Vol.2012 , No.17 , pp.13503 -13529 (Nov, 2012) [논문] 심우영, 김재호, 심점순, 최상돈, Duc-Toan Nguyen, 강진석, 박성수, 백만정, 신은희, 이유원, 이진규, 정학성, 이광, Analysis of changes in gene expression and metabolicprofiles induced by silica-coated magnetic nanoparticles , ACS NANO , Vol.6 , No.9 , pp.7665 -7680 (Sep, 2012) [논문] 권혁권, 박은정, 신현준, 최용민, 최상돈, Doxorubicin Induces Cytotoxicity through Upregulation of pERK?Dependent ATF3 , PLoS ONE , Vol.7 (Sep, 2012) [논문] Basith Shaherin, Balachandran Manavalan, 유태현, 김상건, 최상돈, Roles of Toll-like Receptors in Cancer: A Double-edged Sword for Defense and Offense , ARCHIVES OF PHARMACAL RESEARCH , Vol.35 , No.8 , pp.1297 -1316 (Sep, 2012) [논문] 김범수, 김은영, 김종현, 김혜선, 양명순, 주일로, 최동주, 최상돈, 설원기, 조은혜, Impaired inflammatory responses in murine lrrk2-knockdown brain microglia. , PLoS ONE , Vol.7 , No.4 (Apr, 2012) [논문] 김선아, 박은정, 권혁권, 심우영, 이광, 최용민, 최상돈, Capric Acid Inhibits NO Production and STAT3 Activation during LPS-Induced Osteoclastogenesis , PLoS ONE , Vol.6 , No.11 (Nov, 2011) [논문] 박은정, Jinkyu Roh, Min-Sung Kang, Soo Nam Kim, Younghun Kim, 최상돈, Biological Responses to Diesel Exhaust Particles (DEPs) Depend on the Physicochemical Properties of the DEPs , PLoS ONE , Vol.6 , No.10 (Oct, 2011) [논문] 박은정, Byoung-Seok Lee, Jinkyu Roh, Min-Sung Kang, Soo Nam Kim, Younghun Kim, 최상돈, Biological Toxicity and Inflammatory Response of Semi-Single-Walled Carbon Nanotubes , PLoS ONE , Vol.6 , No.10 (Oct, 2011) [논문] In-Hye Kim, 이수철, 최상돈, Eun-Hye Kim, Sang-Hyun Sohn, Si-Kwan Kim, Suhkneung Pyo, Sung-Won Kim, Dong-Kwon Rhee, Korean Red Ginseng Up-regulates C21-Steroid Hormone Metabolism via Cyp11a1 Gene in Senescent Rat Testes , JOURNAL OF GINSENG RESEARCH , Vol.35 , No.3 , pp.272 -282 (Sep, 2011) [논문] 라쥬, Balachandran Manavalan, Basith Shaherin, 최상돈, Comparative Analysis of Species-Specific Ligand Recognition in Toll-Like Receptor 8 Signaling: A Hypothesis , PLoS ONE , Vol.6 , No.9 (Sep, 2011) [논문] Basith Shaherin, Balachandran Manavalan, 라쥬, 최상돈, In Silico Approach to Inhibition of Signaling Pathways of Toll-Like Receptors 2 and 4 by ST2L , PLoS ONE , Vol.6 , No.8 (Aug, 2011) [논문] 발라, Basith Shaherin, 최상돈, Similar structures but different roles - An updated perspective on TLR structures , Frontiers in Physiology , Vol.2 , No.41 , pp.1 -13 (Jul, 2011) [논문] 발라, 라쥬, 이광, 최상돈, Molecular modeling-based evaluation of dual function of IkBz ankyrin repeat domain in toll-like receptor signaling , JOURNAL OF MOLECULAR RECOGNITION , Vol.4 , pp.597 -607 (Jul, 2011) [논문] Young Taek Oh, 최상돈, 최용민, Anne Jokiaho, Casey Donovan, Insug Kang, Ki-Sook Oh, Jang H. Youn, Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue , Am J Physiol Endocrinol Metab , No.300 (Jun, 2011) [논문] Basith Shaherin, 발라, 이광, 김상건, 최상돈, Toll-like receptor modulators: a patent review (2006 -- 2010) , Expert Opin Ther Pat. , Vol.21 , No.6 , pp.927 -944 (Jun, 2011) [논문] 백만정, 심우영, 김선아, 문승민, 심점순, 최상돈, 김경례, 김동완, 김연미, 이광, Altered Amino Acid Metabolic Patterns in the Plasma of Rat Models with Adenovirus Infection , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.32 , No.5 , pp.1569 -1574 (May, 2011) [논문] Basile T. Siewe, 최상돈, Laurel Druschitz, Pamela L. Witte, Phong T. Le, Simon J. Conway, Susan L. Kalis, Katherine L. Knight, In vitro requirement for periostin in B lymphopoiesis , BLOOD , Vol.14 , pp.3770 -3779 (Apr, 2011) [논문] 백만정, 심우영, 윤재환, 조기홍, 최상돈, 김경례, 또안, 조인선, 이광, Selective 3,4-Dihydroxyphenylalanine Analysis in Human Urine as Ethoxycarbonyltert-butyldimethylsilyl Derivatives by Gas Chromatography-Mass Spectrometry , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.3 , pp.977 -980 (Mar, 2011) [논문] 최상돈, Kang, Insug, Kim, Young I, Oh, Ki-Sook, Oh, Young Taek, Yoon, Hana, Youn, Jang H, Widespread effects of nicotinic acid on gene expression in insulin-sensitive tissues: implications for unwanted effects of nicotinic acid treatment , METABOLISM-CLINICAL AND EXPERIMENTAL , Vol.60 , No.1 , pp.134 -144 (Jan, 2011) [논문] 발라, Basith Shaherin, 이광, 최용민, 최상돈, Structure-Function Relationship of Cytoplasmic and Nuclear IκB Proteins: An in silico analysis , PLoS ONE , Vol.5 , No.12 (Dec, 2010) [논문] 김은영, 권혁권, 김동건, 신혜영, 최용민, 김주영, 이동권, 김유선, 최상돈, ATF3 Plays a Key Role in Kdo2-Lipid A-Induced TLR4-Dependent Gene Expression via NF-κB Activation , PLoS ONE , Vol.5 , No.12 (Dec, 2010) [논문] 백만정, 강현승, 박찬배, 안영환, 이필휴, 최상돈, 이광, Polyamine patterns in the cerebrospinal fluid of patients with Parkinson's disease and multiple system atrophy , CLINICA CHIMICA ACTA , No.411 , pp.1532 -1535 (Oct, 2010) [논문] 라쥬, 발라, 이광, 최상돈, Molecular Modeling-Based Evaluation of hTLR10 and Identification of Potential Ligands in Toll-Like Receptor Signaling , PLoS ONE , Vol.5 , No.9 (Sep, 2010) [논문] Basith Shaherin, 최상돈, This Month in APR - Overview of human cytochrome P450 networks in chemical space , ARCHIVES OF PHARMACAL RESEARCH , Vol.33 , No.9 , pp.1289 -1291 (Sep, 2010) [논문] 발라, Senthil Kumar Muri, 이광, 최상돈, Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases , BMC STRUCTURAL BIOLOGY , Vol.10 , No.1 , pp.1 -14 (Jan, 2010) [논문] 김광수, 최상돈, Joo-Won Jeong, Sunghoi Hong, 김장우, 김한수, 황동윤, Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons , Journal of Neurochemistry , Vol.111 , No.5 , pp.1202 -1212 (Dec, 2009) [논문] 최상돈, 이광, Jayalakshmi Krishnan , Drugs targeting toll-like receptors , ARCHIVES OF PHARMACAL RESEARCH , Vol.32 , No.11 , pp.1485 -1502 (Nov, 2009) [논문] 최상돈, 김정현, 신진영, 심우영, 안영환, 이경아, 이광, 이수철, 박기호, 백만정, Analysis of changes in the viability and gene expression profi les of human mesenchymal stromal cells over time , Cytotherapy , Vol.11 , No.6 , pp.688 -697 (Nov, 2009) [논문] 한상욱, 심우영, 이광, 이상림, 최상돈, 김대용, 김왕준, 김용만, 김현수, 유미현, Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model , JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY , Vol.24 , No.8 , pp.1393 -1400 (Aug, 2009) [논문] 백만정, 안영환, 이필휴, 최상돈, WEN YU LI, 김경래, 김용만, 방오용, 이광, The free fatty acid metabolome in cerebral ischemia following human mesenchymal stem cell transplantation in rats , Clin Chim Acta , Vol.402 , No.1-2 , pp.25 -30 (Apr, 2009) [논문] Tsuchiya, M., 최상돈, Akira, S., Giuliani, A., Piras, V., Selvarajoo, K., Tomita, M., Emergent Genome-Wide Control in Wildtype and Genetically Mutated Lipopolysaccarides-Stimulated Macrophages , PLoS ONE , Vol.4 , No.3 (Mar, 2009) [논문] 최상돈, 이광, Chang, M. S., Santat, L. A., RNAi methodologies for the functional study of signaling molecules , PLoS ONE , Vol.4 , No.2 (Feb, 2009) [논문] 최상돈, K.Jayalakshmi, 이광, 한상욱, Jiayan Chen, Jong-Ik Hwang, Kum-Joo Shin, Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice , Experimental and molecular medicine , Vol.40 , No.5 , pp.495 -504 (Oct, 2008) [논문] 이광, 안영환, 최상돈, Jundong Yu, Man-Bae Hu, Sung-Jean Kim, 김경래, Gas chromatographic-mass spectrometric analyses of cholesterol and its precursors in rat plasma as tert-butyldimethylsilyl derivatives , Clinica Chimica Acta , Vol.396 , pp.62 -65 (Jul, 2008) [논문] 이광, 김훈, 안영환, 조은영, 최상돈, 김경래, Simultaneous clinical monitoring of lactic acid, pyruvic acid and ketone bodies in plasma as methoxime/tert-butyldimethylsilyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode , Biomedical chromatography , Vol.22 , pp.450 -453 (May, 2008) [논문] 이광, 문승민, 안영환, 최상돈, 김경래, Target metabolic profiling analysis of free amino acids in plasma as EOC/TBDMS derivatives by GC-SIM-MS , Biomedical chromatography , Vol.22 , pp.339 -342 (Apr, 2008) [논문] 이광, 계광열, 최상돈, Dong Wan Kim, Hong Ki Jun, Sang Seop Lee, Isolation and characterization of a novel adenosine deaminase inhibitor, IADA-7, from Bacillus sp. J-89 , JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , Vol.14 , No.1 , pp.1 -6 (Mar, 2008) [논문] 최상돈, K.Jayalakshmi, 이광, 한상욱, Characterization of Phototransduction Gene Knockouts Revealed Important Signaling Networks in the Light-Induced Retinal Degeneration , Journal of Biomedicine and Biotechnology , Vol.2008 , No.2008 , pp.1 -7 (Jan, 2008) [논문] Sang Geon Kim, 최상돈, Chang Ho Lee, Jong-Ik Hwang, Min Kyung Cho, Sung Hwan Ki, Won Dong Kim, Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor , Molecular and Cellular Biology , Vol.27 , No.17 , pp.6195 -6208 (Sep, 2007) [논문] 최상돈, K.Jayalakshmi, 이광, Kumar Selvarajoo, Masa Tsuchiya, Toll-like receptor signal transduction , Experimental and Molecular Medicine , Vol.39 , No.4 , pp.421 -438 (Aug, 2007) [논문] 최상돈, Kelly D. Smith, Melvin I. Simon, Mi Sook Chang, Robert C. Hsueh, Ron Taussig, Xiaocui Zhu, Dual Ligand Stimulation of RAW 264.7 Cells Uncovers Feedback Mechanisms That Regulate TLR-Mediated Gene Expression , Journal of Immunology , Vol.177 , No.7 , pp.4299 -4310 (Oct, 2006) [논문] 최상돈, Leah A. Santat, Yeisoo Yu, Bioinformatics packages for sequence analysis , Applied Mycology and Biotechnology , Vol.6 , pp.143 -160 (Sep, 2006) [논문] Winston P. Kuo, 최상돈, Brian Seed, Claudio Punzo, Connie L Cepko, Daniel J Park, Donald McCrann, Eivind Hovig, Fang Liu, George M Church, Glenn F Short III, Jasjit Sarang, Jason Kang, Jeff Trimarchi, Jeffrey R Shearstone, Jocelyn Burke, Ju Han Kim, Kyle Serikawa, Lucila Ohno-Machado, Malini Maysuria, Mark E Whipple, Mason W Freeman, Michael Lombardi, Paola Ricciardi-Cast, Peter Park, Roderick Jensen, Roger Bumgarner, Steven Perrin, Sun Young Lee, Tor-Kristian Jenssen, Trent L Rector, Xiaowei Wang, A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies , Nature Biotechnology , Vol.24 , No.7 , pp.832 -840 (Jul, 2006) [논문] Richard H Scheuerman, 최상돈, Brian Saunders, Dennis Mock, Eva L Rab, Jamie A Lee, Jennifer Cai, Peng Yang, Robert C Hsueh, Robert S Sinkovits, Shankar Subramaniam, Components of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor , BMC bioinformatics , Vol.7 , No.1 , pp.237 -256 (May, 2006) [논문] Jeong Kyo Yoon, 최상돈, Ju-Suk Nam, Peter F. Smith, Taryn J. Turcotte, Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate beta-Catenin-dependent Gene Expression , The Journal of biological chemistry , Vol.281 , No.19 , pp.13247 -13257 (May, 2006) 국내학술논문지 [논문] 백욱영, 이성민, 손인옥, 이상원, 최상돈, 서창희, Intravenous Administration of Toll-Like Receptor Inhibitory Peptide 1 is Effective for the Treatment of Systemic Lupus Erythematosus in a Mus musculus Model , JOURNAL OF RHEUMATIC DISEASES(JRD) , Vol.3 , No.28 (Jul, 2021) [논문] Christine Chung, David A. Newcombe, Mi Sook Chang, Tara Stuecker, 최상돈, Kasthuri Venkateswaran, A Fosmid Cloning Strategy for Detecting the Widest Possible Spectrum of Microbes from the International Space Station Drinking Water System , Genomics & Informatics , Vol.10 , No.4 , pp.249 -255 (Dec, 2012) [논문] Jayalakshmi Krishna, 최상돈, Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling , Genomics & Informatics , Vol.10 , No.3 , pp.153 -166 (Sep, 2012) [논문] 최상돈, TLR, IκB-ζ, ATF3가 출연하는 연구라는 무대의 연출자가 되어 , Molecular and Cellular Biology News , pp.1 -8 (Feb, 2012) [논문] 박지환, 최상돈, Gene Expression Analysis of Gα13-/- Knockout Mouse Embryos Reveals Perturbations in Gα13 Signaling Related to Angiogenesis and Hypoxia , Genomics & Informatics , Vol.9 , No.4 , pp.161 -172 (Dec, 2011) [논문] 김수남, 박은정, 강민성, 김영훈, 김재환, 노진규, 한영아, 최상돈, Toxicity Analysis of Carbon Nanotubes Based on Their Physicochemical Properties , CLEAN TECHNOLOGY , Vol.17 , No.3 , pp.273 -279 (Sep, 2011) [논문] Masa Tsuchiya, 최상돈, Alessandro Giuliani, Kumar Selvarajoo, Masaru Tomita, Naoki Fujikawa, Vincent piras, Statistical Analysis of Gene Expression in Innate Immune Responses: Dynamic Interactions between MicroRNA and Signaling Molecules , Genomics & Informatics , Vol.5 , No.3 , pp.107 -112 (Sep, 2007) [논문] 최상돈, 전호상, Fluorescence Quenching Causes Systematic Dye Bias in Microarray Experiments Using Cyanine Dye , Genomics & Informatic , Vol.5 , No.3 , pp.113 -117 (Sep, 2007) [논문] 최상돈, Construction of Chromosome-Specific BAC Libraries from the Filamentous Ascomycete Ashbya gossypii , Genomics and Informatics , Vol.4 , No.2 , pp.80 -86 (Jun, 2006) [논문] 최상돈, Jeong-Sun Seo, Single and Dual Ligand Effects on Gene Expression Changes in Mouse Macrophage Cells , Genomics and Informatics , Vol.4 , No.2 , pp.57 -64 (Jun, 2006) 국제학술발표 [학술회의] BATOOL MARIA, 최상돈, Evaluation of the Middle East respiratory syndrome coronavirus 4a protein wild type and its mutants binding affinity to dsRNA using steered molecular dynamics simulations , 10th Annual PEGS Europe (Protein & Antibody Enginnering Sumit) (Nov, 2018) [학술회의] PATRA MAHESH CHANDRA, 최상돈, Computational Study of Phosphatidylinositol-Dependent Membrane Localization of Toll/interleukin 1 Receptor Domain-Containing Adaptor Protein , 2018 2nd International Conference on Computational Biology and Bioinformatics (ICCBB 2018) (Oct, 2018) [학술회의] BATOOL MARIA, 최상돈, Identification of Druggable Genome in Staphylococcus aureus Multidrug Resistant Strain , IEEE Life Sciences Conference (Dec, 2017) [학술회의] Muhammad Ayaz Anwar, 최상돈, JAVAID NASIR, Structure-activity relationship in TLR4 mutations and its rectification as a case study in Genome Modification , CRISPR: From Biology to Technology and Novel Therapeutics (Oct, 2017) [학술회의] 신현준, 최상돈, GUI XIANGAI, Evaluation of TLR4 inflammatory pathway using TIRAP-derived peptides , The 56th Midwinter Conference of Immunologists at Asilomar (Jan, 2017) [학술회의] ACHEK ASMA, 최상돈, 신현준, Screening of TLR4 inhibiting peptides using phage display technique , The 56th Midwinter Conference of Immunologists at Asilomar (Jan, 2017) [학술회의] SHAH MASAUD, 최상돈, Muhammad Ayaz Anwar, YESUDHAS DHANUSHA, Structural dynamics of opioid-bound MD2 and the mechanisms of subsequent TLR4 modulation , The 56th Midwinter Conference of Immunologists at Asilomar (Jan, 2017) [학술회의] YESUDHAS DHANUSHA, 최상돈, ANWAR MUHAMMAD AYAZ, PANNERSELVAM SURESH, Transcriptional regulation of Oct4/Sox2 in Hoxb1 and Fgf4 DNA complexes - an in silico approach , International Conference on Biochemistry and Molecular Biology (ICBMB 2016) , pp.15 -15 (Apr, 2016) [학술회의] 신현준, 최상돈, 권혁권, Mechanistic elucidation of etoposide-induced cytotoxicity , Global Conference on Biological Engineering and Natural Science (GCBENS'2016) (Feb, 2016) [학술회의] SHAH MASAUD, 최상돈, ANWAR MUHAMMAD AYAZ, 박설희, A theoretical model of the inhibitory mechanism of IRF3 by HPV-E6 and its species specific drug susceptibility , New Approaches and Concepts in Microbiology (Oct, 2015) [학술회의] Durai Prasannavenkatesh, 최상돈, SAR Study to Synthesize Potential Modulators for Membrane-bound TLR4 Protein , International Conference on Membranes (ICM 2015) (Aug, 2015) [학술회의] ANWAR MUHAMMAD AYAZ, 최상돈, PANNERSELVAM SURESH, SHAH MASAUD, Mechanism of TLR4 modulation using Rhodobacter sphaeroides lipid A using in silico approach , 12th Winter Conference on Medicinal and Bioorganic Chemistry (Jan, 2015) [학술회의] GOSU Vijayakumar, 최상돈, YESUDHAS DHANUSHA, Understanding the Selectivity of TLR7/8 Agonists: an in silico Analysis , International Conference on Host-Pathogen Interactions , pp.112 -112 (Jul, 2014) [학술회의] Durai Prasannavenkatesh, 최상돈, Discovery of Toll-like receptor-2 agonists through Pharmacophore-based Virtual Screening and Biological Evaluation , Interfacing Chemical Biology and Drug Discovery (RICT 2014) (Jul, 2014) [학술회의] 권혁권, 최상돈, 박설희, 신현준, ANTI-APOPTOTIC PROGRAM MEDIATED BY P53 ENHANCES ETOPOSIDE-INDUCED NECROSIS , 7th Asian Pacific Organization for Cell Biology Congress , pp.35 -35 (Feb, 2014) [학술회의] 신현준, 최상돈, 권민철, 권혁권, 박설희, NECROPTOSIS THROUGH PARP1 CAUSES MITOCHONDRIAL HYPER-ACTIVATION AND ROS GENERATION , 7th Asian Pacific Organization for Cell Biology Congress , pp.34 -35 (Feb, 2014) [학술회의] ANWAR MUHAMMAD AYAZ, 최상돈, PANNERSELVAM SURESH, STRUCTURAL DIFFERENCES OF TLR4/MD2 COMPLEX DETERMINE THE AGONIST OR ANTAGONISTIC BEHAVIOR OF RSLA , 7th Asian Pacific Organization for Cell Biology Congress , pp.53 -54 (Feb, 2014) [학술회의] 권민철, 최상돈, 권혁권, 김미현, 김영건, 박설희, 신현준, MITOCHONDRIAL PHYSIOLOGY IS DIFFERENTIALLY INFLUENCED BY DOXORUBICIN OR ETOPOSIDE TREATMENT , 7th Asian Pacific Organization for Cell Biology Congress , pp.36 -36 (Feb, 2014) [학술회의] 박설희, 최상돈, 권민철, 권혁권, 신현준, INSIGHT INTO THE ETOPOSIDE TOXICITY: ETOPOSIDE INDUCES CYTOTOXICITY VIA ROS/ERK/ATF3 PATHWAY IN HK-2 , 7th Asian Pacific Organization for Cell Biology Congress , pp.35 -36 (Feb, 2014) [학술회의] YESUDHAS DHANUSHA, 최상돈, Basith Shaherin, PANNERSELVAM SURESH, Insight into the Binding Mode Analysis of Combinatorial Cancer Drugs with Cytochrome P450 , Translational Bioinformatics Conference -TBC/ISCB-Asia 2013 , pp.54 -54 (Oct, 2013) [학술회의] PANNERSELVAM SURESH, 최상돈, Basith Shaherin, Docking analysis of selective combinatorial drugs with Cytochrome P450 in cancer therapy , The XIII International Congress of Toxicology (Jul, 2013) [학술회의] GOSU Vijayakumar, 최상돈, Molecular Dynamics Simulations and Normal Mode Analysis of IRAK Proteins , International Conference on Bioengineering , pp.182 -182 (Jan, 2013) [학술회의] Durai Prasannavenkatesh, 최상돈, Toward a better understanding of the interaction between malarial GPIs and TLR2 subfamily: A computational study , International Conference on Bioengineering , pp.184 -184 (Jan, 2013) [학술회의] GOSU Vijayakumar, 최상돈, Phylogenetic and Functional Divergence Analysis of Vertebrate IRAK Family Members , ACM-BCM 2012 (Oct, 2012) [학술회의] Basith Shaherin, 최상돈, An in-depth analysis of the molecular dynamics and structural aspects of IκB proteins , ACM-BCM 2012 (Oct, 2012) [학술회의] GOSU Vijayakumar, 최상돈, Evolutionary and Functional Divergence Interplay among Verterbrate IkB Family Members , International Conference - Molecular Ecology (Feb, 2012) [학술회의] 권혁권, 최상돈, 최용민, Cisplatin induced nephrotoxicity via ATF3 , The 51st Midwinter Conference of Immunologists (Jan, 2012) [학술회의] 최용민, 최상돈, Basith Shaherin, 권혁권, Induction of chemokines mediated by TNF-a in TRAF6 deficient cells , The 51st Midwinter Conference of Immunologists (Jan, 2012) [학술회의] 김한결, 최상돈, 권혁권, 최용민, Cisplatin induced cell cycle arrest through CDKN1A, CDKN2B and CDKN2 , The 51st Midwinter Conference of Immunologists (Jan, 2012) [학술회의] 라쥬, 최상돈, Understanding the binding mode and function of GPIs of Plasmodium falciparum with TLR2 complexes , Molecular Life Science 2011 (Sep, 2011) [학술회의] YOUNGTAEK OH, JANG H. YOUN , 최상돈, 최용민, INSUG KANG, KI-SOOK OH, Continuous Nicotinic Acid Infusion in Rats Causes FFA Rebound by Altering Gene Expression and Increasing Basal Lipolysis in Adipose Tissue , 71st Scientific Sessions (Jun, 2011) [학술회의] 이수철, 최상돈, 신혜영, Cellular Network Analysis of Cisplatin-Induced Renal Toxicity , 4th AYRCOB , pp.11 -11 (Dec, 2010) [학술회의] 발라, 최상돈, Structure-Function Relationship of Cytoplasmic and Nuclear IκB proteins: Structural flexibility contributes to functional divergence , Systems Biology - Regulatory Genomics - DREAM5 2010 , pp.150 -150 (Nov, 2010) [학술회의] 라쥬, 최상돈, Insilico analysis of species-specific ligand recognition in Toll like receptor 8 signaling , Systems Biology - Regulatory Genomics - DREAM5 2010 , pp.133 -133 (Nov, 2010) [학술회의] Basith Shaherin, 최상돈, Computational approach for the identification of the ST2L inhibitory hotspots on MyD88-dependent TLR2 and TLR4 Signaling Pathways , Systems Biology - Regulatory Genomics - DREAM5 2010 , pp.118 -118 (Nov, 2010) [학술회의] 라쥬, 최상돈, 이광, Structural analysis of ligand induced homo dimerization in Toll like receptor 9 signaling , 4th International Symposium on Recent Trends in Macromolecular Structure and Function (Jan, 2010) [학술회의] 발라, 최상돈, 이광, Molecular modeling-based evaluation of dual function of IkBzeta in Toll-like receptor signaling , 4th International Symposium on Recent Trends in Macromolecular Structure and Function (Jan, 2010) [학술회의] 최상돈, Systemic biology approaches for the study of innate immunity , 2009 JST-KICOS Corrperative Programme of IFReC and IVI , Vol.1 , No.4 , pp.40 -40 (Sep, 2009) [학술회의] 최상돈, 이광, The Free Fatty Acid Metabolome in Cerebral Ischemia Following Human Mesenchymal Stem Cell Transplantation in Rats , Stem Cells World Congress , Vol.2009 , No.2009 , pp.5 -5 (Jan, 2009) [학술회의] 최상돈, Systems Biology Approaches: Solving new puzzles with old clues , Integrated Approach to Personalized Medicine , pp.15 -15 (Dec, 2008) [학술회의] 최상돈, Senthil, 발라, 이광, IκB-ζ provides a specific scaffold for the recruitment of p65 and p50 subunits of NF-ĸB and explains the mechanism of inhibition and transactivation , The 9th International Congress on Cell Biology , No.17 , pp.377 -377 (Oct, 2008) [학술회의] 최상돈, Senthil Kumar Muri, 박지환, 발라, 이광, 한상욱, Gene expression analyses of Gα13-/- knockout embryos and embryonic fibroblasts exhibit the important role of Gα13 in angiogenesis signaling , The 9th International Congress on Cell Biology , No.17 , pp.1 (Oct, 2008) [학술회의] 최상돈, K.Jayalakshmi, 이광, 황종익, Multiligand stimulation of TLRs identifies that RELA, FOS and IRF1 enhanceosome complex is indispensable for gene induction , The 9th International Congress on Cell Biology , No.17 , pp.377 -377 (Oct, 2008) [학술회의] 최상돈, Systems Approaches to Biology and Medicine , The 9th International Congress on Cell Biology , No.17 , pp.190 -190 (Oct, 2008) [학술회의] 이동권, 이수철, 최상돈, 김혜은, 이미정, Systems Biology Analysis of Ginseng Effects on Immobilization Stressed Mice Brain and PADI4 and SLC4A1 as Stress Markers , The 9th International Congress on Cell Biology , No.2 , pp.372 -372 (Oct, 2008) [학술회의] 최상돈, Jaya, Senthil, 라쥬, 발라, 이광, Molecular modeling of TLR10-TLR10 and TLR10-TLR2 , The 9th International Congress on Cell Biology , No.17 , pp.378 -378 (Oct, 2008) [학술회의] 최상돈, K.Jayalakshmi, 이광, 이수철, 김은혜, 이동권, ATF3 KO triggers robust antiviral responses in MEF cells , The 9th International Congress on Cell Biology , No.17 , pp.1 (Oct, 2008) [학술회의] 최상돈, K.Jayalakshmi, 김은영, 이광, 이수철, 최용민, 김은혜, 이동권, ATF3 Regulates Cell Cycle by Reducing SCF Expression in Mouse Embryonic Fibroblast Cells Treated with LPS , The 9th International Congress on Cell Biology , No.17 , pp.1 (Oct, 2008) [학술회의] 최상돈, Senthil, 민철기, 박지환, 이광, 최동순, Differential regulation of TNF signaling pathways by CD40L and AIG , The 9th International Congress on Cell Biology , No.17 , pp.1 (Oct, 2008) [학술회의] Kumar Selvarajoo, 최상돈, Alessandro Giuliani, Masa Tsuchiya, Masaru Tomita, Shizuo Akira, Vincent Piras, Multi-layer differential activation of biological processes in LPS-stimulated macrophages , The 9th International Conference on Systems Biology , No.1-102 , pp.117 -117 (Aug, 2008) [학술회의] 최상돈, Systems Approaches to Biology after the Genome Projects , UKC 2008 , No.2.2 , pp.26 (Aug, 2008) [학술회의] 최상돈, K.Jayalakshmi, 최용민, CD40L and IL-4 specifically regulate the key signal transduction genes in murine splenic B cells , Genetic Analysis: Model Organisms to Human Biology , Vol.197 , pp.88 (Jan, 2008) [학술회의] 최상돈, K.Jayalakshmi, Transcriptional regulation of immune responses after the activation of different TLRs in murine macrophage RAW 264.7 cells , Genetic Analysis: Model Organisms to Human Biology , Vol.213 , pp.94 (Jan, 2008) [학술회의] 최상돈, Introduction to Systems Biology , 2007 대한생화학분자생물학회 추계 국제학술대회 , No.7-4 , pp.51 -51 (Oct, 2007) [학술회의] 최상돈, K.Jayalakshmi, 이광, 한상욱, Signaling Networks Involved in Retinal Degeneration in Mice , FBIT 2007 , Vol.2007 , pp.10 -10 (Oct, 2007) [학술회의] 최상돈, K.Jayalakshmi, 김샛별, Estelle Wall, Iain Fraser, Joelle Zavzavadjian, Jong-ik Hwang, Leah Santat, Mi Sook Chang, Pamela Eversole-Cire, Robert Rebres, Tamara Roach, Silencing the expression of G proteins by siRNAs, shRNA or ASO in mouse macrophage RAW 264.7 cells , 19th FAOBMB Seoul Conference , Vol.19 , pp.4 -4 (May, 2007) [학술회의] 최상돈, K.Jayalakshmi, 김샛별, TLR and non-TLR ligands induced non-additive transcriptional responses in murine RAW 264.7 cells , 19th FAOBMB Seoul Conference , Vol.19 , pp.2 -2 (May, 2007) [학술회의] 최상돈, K.Jayalakshmi, 김샛별, 최용민, Crosstalk signaling points between CD40L and IL-4 in mouse B cells , 19th FAOBMB Seoul Conference , Vol.19 , pp.12 -12 (May, 2007) [학술회의] 최상돈, Felix N. Lee, Jang H. Youn, Mi S. Chang, Woo S. Choi, Young I. Kim, FOXO1 Dependent and Independent Effects of Nicotinic Acid on Gene Expression in Insulin Sensitive Tissues , American Diabetes Association 66th Scientific Sessions , No.1060 , pp.1 -1 (Jun, 2006) [학술회의] 최상돈, Felix N. Lee, Jang H. Youn, Mi S. Chang, Young I. Kim, Regulation of Slow-Fiber-Specific Gene Expression in Skeletal Muscle by Plasma FFA Level , American Diabetes Association 66th Scientific Sessions , No.1454 , pp.1 -1 (Jun, 2006) [학술회의] 최상돈, Christine Chung, David A. Newcombe, Kasthuri Venkateswar, Mi Sook Chang, Tara Stuecker, Fosmid cloning strategy for detection of the widest possible spectrum of microbes from the International Space Station drinking water system , American Society for Microbiology 106th General Meeting , pp.1 -1 (May, 2006) 국내학술발표 [학술회의] Sang-Joon CHO, 최상돈, 권혁권, Myunghoon CHOI, Monitoring of nucleus changes upon cell death using atomic force microscopy and ion conductance microscopy , 2016년 한국진공학회 IVC-20 (Aug, 2016) [학술회의] 최상돈, Pharmacophore ?based virtual studies and their experimental validation , 2016 KSBMB(Korean Society for Biochemistry and Molecular Biology) Winter Workshop (Jan, 2016) [학술회의] 최상돈, The Guardian of Necrosis and Apoptosis : p53 , 동물 모델에서 PLC 기능 연구 및 유전자 변이탐색 - UNIST C5 Center Symposium (Sep, 2013) [학술회의] 최상돈, Molecular Mechanisms of Cytotoxicity and Cell Death Induced by Anticancer Drugs , 2013 KOGO 22nd Annual Conference - Next Generation Translational Genomics , pp.53 -53 (Sep, 2013) [학술회의] 박설희, 최상돈, 권민철, 권혁권, 신현준, 이진선, Etoposide Induces Renal Dysfunction via H2O2/ERK/ATF3 Pathway , 2013 KOGO 22nd Annual Conference - Next Generation Translational Genomics , pp.134 -134 (Sep, 2013) [학술회의] 조혜영, 최상돈, ANWAR MUHAMMAD AYAZ, 권혁권, 김한결, 최용민, ATF3 prevents cyclosporin A induced nephrotoxicity by down-regulation of CHOP in HK-2 cells , 2013 KSBMB Annual Meeting (May, 2013) [학술회의] 권지웅, 최상돈, ANWAR MUHAMMAD AYAZ, 최용민, ATF3 targets IκBζ to attenuate IL-6 expression in TLR pathways , 2013 KSBMB Annual Meeting (May, 2013) [학술회의] 신현준, 최상돈, PANNERSELVAM SURESH, 권혁권, 최용민, Different cytotoxic effects of p53 phosphorylation in the treatments with anticancer drugs , 2012 KSMCB (Oct, 2012) [학술회의] 권민철, 최상돈, PANNERSELVAM SURESH, 권혁권, 박설희, 신현준, 최용민, A key role of p53 phosphorylation in etoposide-induced cytotoxicity , 2012 KSMCB (Oct, 2012) [학술회의] Basith Shaherin, 최상돈, Molecular dynamic and structural aspects of IkB proteins: An in-depth analysis , 2012 KSBMB (Jun, 2012) [학술회의] 박은정, 최상돈, 권혁권, 최용민, Doxorubicin induces acute renal failure via acidosis , 한국분자세포생물학회 정기학술대회 (Oct, 2011) [학술회의] 박은정, 최상돈, Kang Min-Sung, Kim Soo Nam, Kim Younghun, Lee Byoung-Seok, Roh Jinkyu, Biological Toxicity and Inflammation Response of Semi-Single-Walled Carbon Nanotubes , 한국분자세포생물학회 정기학술대회 (Oct, 2011) [학술회의] 최용민, 최상돈, 권혁권, 박은정, Doxorubicin induces nephrotoxicity through the up-regulation of p-ERK-dependent ATF3 , 한국분자세포생물학회 정기학술대회 (Oct, 2011) [학술회의] 최상돈, Network analysis for the prediction and evaluation of target organ toxicity , 2011 Workshop on Green Toxicology & Technology for Prediction of Target Organ Toxicity (Mar, 2011) [학술회의] 이수철, 최상돈, 김유선, 김은영, 라쥬, 발라, 신혜영, Starting from the Network Analysis to the Control of Innate Immunity , Informatics-Inspired Molecular and Clinical Research , pp.73 -82 (Dec, 2010) [학술회의] 윤지수, 최상돈, 이광, 이지윤, THE HSC70/CHIP UBIQUTIN LIGASE COMPLEX TARGETS NON-GLYCOSYLATED BCRP TO ER-ASSOCIATED DEGRADATION(ERAD) , 제62차 대한약리학회 추계학술대회 , pp.136 -136 (Oct, 2010) [학술회의] 라쥬, 최상돈, 발라, 이광, Molecular modeling based to evaluate the function of hTLR10 homo and hetero dimerization in Toll like receptor signaling , 2010 Bioscience for the Better Life , pp.320 -320 (May, 2010) [학술회의] 신혜영, 최상돈, 권혁권, 김재헌, 최용민, ATF3 regulates TLR 9-mediated IL-6 production via activation of NF-kB and MAPKs , 2010 Bioscience for the Better Life , pp.335 -335 (May, 2010) [학술회의] 심우영, 이광, 김선아, 백만정, 최상돈, Analysis of amino acid metabolic profiling in the plasma of rat models with adenovirus infection , 2010 Bioscience for the Better Life (May, 2010) [학술회의] 윤지수, 이지윤, 최상돈, 최철희, Jab1/CSN5 mediates ER-associated degradation (ERAD) of immature BCRP , 2010 Bioscience for the Better Life , pp.444 -444 (May, 2010) [학술회의] 최상돈, Systems Biology Approaches for Green Pharm , Omics to Personal Medicine , Vol.18 , No.18 , pp.86 -86 (Sep, 2009) [학술회의] 이동권, 최상돈, Suhkneung Pyo, Thao Dang-Hien Tran, Tu Nhat Le, 김은혜, 정경태, Systems Biology Analysis of Streptococcus Pneumoniae Invation into A549 Human Cells and Activation of Small Rho-GTPases via Rap1 in a ClpL-Dependent Manner , Omics to Personal Medicine , Vol.18 , No.18 , pp.84 -84 (Sep, 2009) [학술회의] 최상돈, Systems Biology Approaches: Solving New Puzzles with Old Clues , New Technology and Methods in Molecular Medicine , Vol.2009 , No.2009 , pp.121 -131 (Sep, 2009) [학술회의] 최상돈, Systems biological approaches for the study of cellular signaling in immune cell , Microbial Pathogenesis and Immunity Symposium , Vol.1 , No.1 , pp.43 -56 (Jun, 2009) [학술회의] 최상돈, 김유선, 김은영, 이광, ATF3 plays a key role in Kdo2-Lipid A induced TLR4 dependent gene expression , From Molecules to Diseases , Vol.17 , No.421 , pp.341 -341 (Apr, 2009) [학술회의] 최상돈, 발라, 이광, Molecular modeling of reductase domain highlights an alternate reaction mechanism in non-ribosomal peptide synthetases , From Molecules to Diseases , Vol.17 , No.324 , pp.293 -293 (Apr, 2009) [학술회의] 최상돈, 여말희, 이광, 조성원, 최용민, 자야, 정재윤, Gene Expression Profiling of CLD and HCC in HBV-Associated Liver Diseases , From Molecules to Diseases , Vol.17 , No.513 , pp.387 -387 (Apr, 2009) [학술회의] 이광, Wen Yu Li, 안영환, 최상돈, 김경래, 방오영, 백만정, 이필휴, Study on Fatty Acid metabolism in Cerebral Ischemia Rat Model Following Human Mesenchymal Stem Cell Transplantation , From Molecules to Diseases , Vol.17 , No.543 , pp.402 -402 (Apr, 2009) [학술회의] 최상돈, Systems Biology: Association of a puzzle to the fact which you ignored in the old days , 2008 KRIBB CONFERENCE , pp.18 -18 (Nov, 2008) [학술회의] 최상돈, Comparison of various RNAi Methodologies for Gene Silencing , The 17th KOGO Conference , No.4 , pp.22 -22 (Sep, 2008) [학술회의] 최상돈, K.Jayalakshmi, 발라, 이광, Systems biology approaches identify IkBzeta as the transactivator of IL-6 and co-regulated genes during LPS signaling in RAW 264.7 cells , KSBMB Annual Meeting , No.20 , pp.319 -319 (May, 2008) [학술회의] 최상돈, Senthil, 박지환, 이광, Microarray analysis of Gα13-/- knockout embryos reveals perturbations in Gα13 signaling related to hypoxia and angiogenesis , KSBMB Annual Meeting , No.16 , pp.318 -318 (May, 2008) [학술회의] 이광, 심우영, 최상돈, 최용민, Analysis of gene expression profiling in MNP treated cells and in vivo tracking system research , KSBMB Annual Meeting , No.29 , pp.226 -226 (May, 2008) [학술회의] 최상돈, Systems Approaches to Biology and Medicine , IDRC International Symposium , Vol.1 , pp.12 -13 (Apr, 2008) [학술회의] 최상돈, Construction of Cellular Signaling Networks in Murine Macrophage , Functional Genomics for Model Organisms , Vol.2007 , No.2007 , pp.12 -12 (Nov, 2007) [학술회의] 최상돈, K.Jayalakshmi, 최용민, CD40L and IL-4 Signaling Crosstalk Points in Murine B Cells , Omics to Industry , Vol.16 , pp.11 -11 (Sep, 2007) [학술회의] 최상돈, A systems biological approach of EMT , EMT and Systems Biology , Vol.1 , No.1 , pp.39 -39 (May, 2007) 저서 및 번역 [저서] 최상돈, Balachandran Manavalan, Shaherin Basith, [book chapter] MyD88 (Myeloid Differentiation Primary Response Gene 88) (Mar, 2018) [저서] 최상돈, Muhammad Ayaz Anwar, Receptor-Interacting Protein Kinase (Mar, 2018) [저서] 최상돈, Muhammad Ayaz Anwar, Jayalakshmi Krishnan, [book chapter] TLR4 (Toll-Like Receptor 4) (Mar, 2018) [저서] 최상돈, Encyclopedia of Signaling Molecules (Mar, 2018) [저서] 최상돈, Durai Prasannavenkatesh, Toll-Like Receptor 2 (Mar, 2018) [저서] 최상돈, Shah Masaud, Interferon Regulatory Factor (Mar, 2018) [저서] Nima Rezaei, Basith Shaherin, 최상돈, Seyed Hossein Aalaei-Andabili , Cancer Immunology - Toll-Like Receptor Pathway and its Targeting in Treatment of Cancers , pp.329-339 (Jan, 2015) [저서] 최상돈, Immuno Systems Biology (Oct, 2013) [저서] 최상돈, Durai Prasannavenkatesh, Rajiv Gandhi, Kidney -Chapter 5. In Silico Approaches to Study Drug-induced Renal Toxicity- , pp.103-120 (Sep, 2013) [저서] Jayalakshmi Krishna, 최상돈, TLR4, Toll-Like Receptor 4 (Sep, 2012) [저서] 최상돈, Encyclopedia of Signaling Molecules (Sep, 2012) [저서] Basith Shaherin, 최상돈, Balachandran Manavalan, MyD88, Myeloid Differentiation Primary Response Gene 88 (Sep, 2012) [저서] Balachandran Manavalan, 최상돈, Basith Shaherin, IkBz (Sep, 2012) [저서] 최상돈, Systems Biology for Signaling Networks (Aug, 2010) [저서] 최상돈, Balsa-Canto, Banga, Baranova, Batzoglou, Birerdinc, Bivort, Brinkman, Brock, Chaouiya, Chen, Chen, Chu, Cooling, Daigle, Jr., Daleo, Dematte, Dittrich, Dozmorov, Drager, Dzeroski, Erhard, Estep, Fjell, Flannick, Franks, Freeman, Friedel, Gardy, Geschwind, Glazar, Hancock, Hao, Helikar, Hiroko Kozuka-Hata, Hong, Huan, Hurst, Jiang, Koch, Kochi, Kolaczyk, Konvalina, Larcher, Li, Lynn, Mete, Miller, Muller, Nikolov, Noirel, Novak, Oyama, Palmer, Palmisano, Priami, Ram, Rogers, Romanel, Rutherford, Ruxton, Sanguinetti, Schroder, Sealfon, Sealfon, Segota, Sinzinger, Srinivasan, Tang, Tasaki, Todorovski, Vera, Vlahovicek, Wolkenhauer, Wright, Xu, Younossi, Yu, Yuruk, Zell, Zimmer, Systems Biology Approaches: Solving New Puzzles in a Symphonic Manner , pp.3-11 (Aug, 2010) [저서] 홍영남, 김한집, 김혜선, 남석현, 도수일, 문은표, 민철기, 박상규, 이종수, 최상돈, 강혜순, 고영규, 고용, 권윤의, 김기중, 김영환, 김은수, 김재진, 김정국, 김준, 박선우, 박세호, 박용근, 박우준, 신숙, 신정섭, 안지훈, 안태인, 오승은, 이경호, 이명민, 이봉희, 이상임, 이태호, 이호정, 장태용, 조면행, 조진원, 생명과학 (Mar, 2009) [저서] 최상돈, Introduction to Systems Biology (Aug, 2007)
특허 및 기타	[특허] 최상돈, CXCR4와 상호작용하여 줄기세포 이동을 유도하는 신규한 SDP-4 펩타이드 (등록) (10-2604981) (Nov, 2023) [특허] 최상돈, RATHER BILAL AHMAD, 염증성 질환 치료를 위한 NLRP3 인플라마좀 억제 펩타이드 (출원) (18/279,772) (R0420US) (Aug, 2023) [특허] 최상돈, RATHER BILAL AHMAD, 염증성 질환 치료를 위한 NLRP3 인플라마좀 억제 펩타이드 (출원) (22792029.5) (R0420EP) (Aug, 2023) [특허] 최상돈, HASEEB MUHAMMAD, JAVAID NASIR, YASMEEN FARZANA, 알츠하이머병 치료를 위한 NLRP3 인플라마좀 소분자 억제제 (출원) (22749988.6) (R0420EP) (Aug, 2023) [특허] 최상돈, HASEEB MUHAMMAD, JAVAID NASIR, YASMEEN FARZANA, 알츠하이머병 치료를 위한 NLRP3 인플라마좀 소분자 억제제 (출원) (18/275,470) (R0420US) (Aug, 2023) [특허] 김현아, 안미현, 최상돈, 최양선, 자기염증질환의 예방 또는 치료용 조성물 및 이의 용도 (출원) (PCT/KR2023/011093) (Jul, 2023) [특허] 최상돈, JAVAID NASIR, CRISPR/Cas 시스템을 이용한 유도만능 줄기세포 제조방법 (출원) (18/268,894) (R0420US) (Jun, 2023) [특허] 김현아, 안미현, 최상돈, 최양선, 자기염증질환 치료 및 예방 조성물 (출원) (10-2023-0073942) (Jun, 2023) [특허] 최상돈, 톨-유사 수용체 1/2 및/또는 4 활성화 펩타이드 및 이의 용도 (등록) (10-2543157) (Jun, 2023) [특허] 최상돈, 포밀 펩타이드 수용체에 결합하는 줄기세포 이동용 펩타이드 (등록) (10-2537675) (May, 2023) [특허] 최상돈, FAROOQ MARIYA, RATHER BILAL AHMAD, 자가면역 질환 치료를 위한 신규 MyD88 억제제 및 이의 용도 (출원) (10-2023-0066446) (May, 2023) [특허] 최상돈, 김은하, 톨-유사 수용체 3/7/8/9 억제 기능이 있는 길항성 소분자 화합물 TAC5 시리즈 (등록) (11,629,155) (R0420US) (Apr, 2023) [특허] 최상돈, CXCR4와 상호작용하여 줄기세포 이동을 유도하는 신규한 펩타이드 (등록) (10-2515415) (Mar, 2023) [특허] 최상돈, JAVAID NASIR, CRISPR/Cas 시스템을 이용한 유도만능 줄기세포 제조방법 (등록) (10-2494508) (Jan, 2023) [특허] 최상돈, 김재선, 유형철, 톨-유사 수용체 7/9 억제 기능이 있는 길항성 소분자 화합물 (출원) (21800188.1) (R0420EP) (Dec, 2022) [특허] 최상돈, PDGF 유래 신규 펩타이드 및 이의 용도 (출원) (10-2022-0152821) (Nov, 2022) [특허] 최상돈, 김재선, 유형철, 톨-유사 수용체 7/9 억제 기능이 있는 길항성 소분자 화합물 (출원) (17/923,061) (R0420US) (Nov, 2022) [특허] 최상돈, BATOOL MARIA, JAVAID NASIR, PATRA MAHESH CHANDRA, 함대현, 종양 괴사 인자 알파(TNF-α) 소분자 억제제 (출원) (17/774,346) (R0420US) (May, 2022) [특허] 최상돈, RATHER BILAL AHMAD, 염증성 질환 치료를 위한 NLRP3 인플라마좀 억제 펩타이드 (출원) (PCT/KR2022/005662) (Apr, 2022) [특허] 최상돈, HASEEB MUHAMMAD, PATRA MAHESH CHANDRA, 최양선, TLR7 및 TLR9의 신호전달 경로를 억제하는 신규한 소분자 화합물 및 그 용도 (출원) (20847286.0) (R0420EP) (Feb, 2022) [특허] 최상돈, HASEEB MUHAMMAD, JAVAID NASIR, YASMEEN FARZANA, 알츠하이머병 치료를 위한 NLRP3 인플라마좀 소분자 억제제 (출원) (PCT/KR2022/001620) (Jan, 2022) [특허] 최상돈, HASEEB MUHAMMAD, PATRA MAHESH CHANDRA, 최양선, TLR7 및 TLR9의 신호전달 경로를 억제하는 신규한 소분자 화합물 및 그 용도 (출원) (17/630,043) (R0420US) (Jan, 2022) [특허] 최상돈, JAVAID NASIR, CRISPR/Cas 시스템을 이용한 유도만능 줄기세포 제조방법 (출원) (PCT/KR2021/019696) (Dec, 2021) [특허] 김문석, SHAH MASAUD, 박승훈, 최상돈, 전구세포 또는 줄기세포 동원 활성을 가지는 물질 P 유사체 및 이를 포함하는 조성물 (등록) (11,186,612) (R0420US) (Nov, 2021) [특허] 최상돈, PDGF 유래 신규 펩타이드 및 이의 용도 (출원) (10-2021-0143554) (Oct, 2021) [특허] 최상돈, EGF 유래 신규 펩타이드 및 이의 용도 (출원) (10-2021-0143570) (Oct, 2021) [특허] 최상돈, BMP 유래 신규 펩타이드 및 이의 용도 (출원) (10-2021-0141771) (Oct, 2021) [특허] 최상돈, 김재선, 유형철, 톨-유사 수용체 7/9 억제 기능이 있는 길항성 소분자 화합물 (출원) (PCT/KR2021/005624) (May, 2021) [특허] 최상돈, RATHER BILAL AHMAD, 염증성 질환 치료를 위한 NLRP3 인플라마좀 억제 펩타이드 (출원) (10-2021-0050985) (Apr, 2021) [특허] 최상돈, 김은하, 서창희, 톨-유사 수용체 3/7/8/9 억제 기능이 있는 길항성 소분자 화합물 TAC5 시리즈 (등록) (10-2234399) (Mar, 2021) [특허] 최상돈, HASEEB MUHAMMAD, JAVAID NASIR, YASMEEN FARZANA, 알츠하이머병 치료를 위한 NLRP3 인플라마좀 소분자 억제제 (출원) (10-2021-0015425) (Feb, 2021) [특허] 최상돈, 백욱영, 서창희, 정의석, 최양선, 엔도솜 톨-유사 수용체를 제어하는 신규 소분자 화합물 및 이를 이용한 자가면역질환 치료제 (출원) (10-2020-0160977) (Nov, 2020) [특허] 최상돈, BATOOL MARIA, JAVAID NASIR, PATRA MAHESH CHANDRA, 함대현, 종양 괴사 인자 알파(TNF-α) 소분자 억제제 (출원) (PCT/KR2020/015359) (Nov, 2020) [특허] 김문석, SHAH MASAUD, 박승훈, 최상돈, 전구세포 또는 줄기세포 동원 활성을 가지는 물질 P 유사체 및 이를 포함하는 조성물 (등록) (10-2171363) (Oct, 2020) [특허] 최상돈, 신규한 TLR2 길항제 (등록) (3305767) (R0420EP) (Sep, 2020) [특허] 최상돈, PATRA MAHESH CHANDRA, 최양선, 신규한 톨-유사 수용체 3/7/9 억제 소분자 화합물 (출원) (10-2020-0093597) (Jul, 2020) [특허] 최상돈, HASEEB MUHAMMAD, PATRA MAHESH CHANDRA, 최양선, TLR7 및 TLR9의 신호전달 경로를 억제하는 신규한 소분자 화합물 및 그 용도 (출원) (PCT/KR2020/009732) (Jul, 2020) [특허] 최상돈, ACHEK ASMA, SHAH MASAUD, 김기영, 김순선, 김욱, 서창희, 정재연, 자가면역질환 및 염증성질환 펩타이드 치료제 (출원) (PCT/KR2020/008536) (Jun, 2020) [특허] 최상돈, 김재선, 유형철, 톨-유사 수용체 7/9 억제 기능이 있는 길항성 소분자 화합물 (출원) (10-2020-0053335) (May, 2020) [특허] 김문석, 김민주, 박승훈, 서지영, 최상돈, 염증 억제 펩타이드의 물리적/화학적 함유 주사 제형 전달체, 이의 제조 방법 및 응용 (등록) (10-2088107) (Mar, 2020) [특허] 최상돈, BATOOL MARIA, JAVAID NASIR, PATRA MAHESH CHANDRA, 함대현, 종양 괴사 인자 알파(TNF-α) 소분자 억제제 (출원) (10-2019-0140132) (Nov, 2019) [특허] 최상돈, GUI XIANGAI, 권혁권, 서창희, 신현준, TLR 억제 펩타이드를 포함하는 루푸스 예방 또는 치료용 조성물 (출원) (PCT/KR2019/014728) (Nov, 2019) [특허] 최상돈, HASEEB MUHAMMAD, PATRA MAHESH CHANDRA, 최양선, TLR7 및 TLR9의 신호전달 경로를 억제하는 신규한 소분자 화합물 및 그 용도 (출원) (10-2019-0090580) (Jul, 2019) [특허] 최상돈, ACHEK ASMA, SHAH MASAUD, 김기영, 김순선, 김욱, 서창희, 정재연, 자가면역질환 및 염증성질환 펩타이드 치료제 (출원) (10-2019-0085927) (Jul, 2019) [특허] 최상돈, 신규한 TLR2 길항제 (등록) (10,308,655) (R0420US) (Jun, 2019) [특허] 최상돈, 김은하, 톨-유사 수용체 3/7/8/9 억제 기능이 있는 길항성 소분자 화합물 TAC5 시리즈 (출원) (PCT/KR2019/005978) (May, 2019) [특허] 김문석, 최상돈, 박용두, 장환석, 프로그래밍 알고리즘 및 수치 해석을 이용한 전구세포 또는 줄기세포 동원활성을 가지는 물질의 동원활성에 대한 정량적 평가 방법 (출원) (10-2019-0058009) (May, 2019) [특허] 최상돈, ACHEK ASMA, TLR4 신호전달 경로를 억제하는 펩타이드 및 그 용도 (출원) (10-2019-0000630) (Jan, 2019) [특허] 최상돈, Durai Prasannavenkatesh, SHAH MASAUD, 신현준, 중동호흡기증후군 코로나바이러스 감염증 예방 또는 치료용 조성물 (등록) (10-1934199) (Dec, 2018) [특허] 최상돈, GUI XIANGAI, 권혁권, 서창희, 신현준, TLR 억제 펩타이드를 포함하는 루푸스 예방 또는 치료용 조성물 (출원) (10-2018-0133679) (Nov, 2018) [특허] 최상돈, GUI XIANGAI, 권혁권, 신현준, 톨-유사 수용체(TLR) 억제를 위한 펩타이드 및 이를 포함하는 약학적 조성물 (출원) (10-2018-0046715) (Apr, 2018) [특허] 최상돈, 신규한 TLR4 길항제 (출원) (15894332.4) (R0420EP) (Dec, 2017) [특허] 최상돈, 신규한 TLR4 길항제 (출원) (15/578,094) (R0420US) (Nov, 2017) [특허] 최상돈, 신규한 TLR4 길항제 (출원) (201580080526.8) (R0420CN) (Nov, 2017) [특허] 최상돈, 신규한 TLR4 길항제 (출원) (2017-562335) (R0420JP) (Nov, 2017) [특허] 최상돈, 신규한 TLR2 길항제 (등록) (10-1745524) (Jun, 2017) [특허] 최상돈, 신규한 TLR2 길항제 (출원) (PCT/KR2015/014202) (Dec, 2015) [특허] 최상돈, 신규한 TLR4 길항제 (출원) (PCT/KR2015/008055) (Jul, 2015) [특허] 최상돈, 독성 예측 및 치료 타겟으로서의 ＡｃｔｉｖａｔｉｎｇＴｒａｎｓｃｒｉｐｔｉｏｎＦａｃｔｏｒ３（ＡＴＦ３） (등록) (10-1356811) (Jan, 2014)

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